Sporotrichosis

Figure 4.30 A: Sporothrix schenckii (Courtesy of Sandra Arduin, Michigan Department of Community Health) B: Coccidioidomycosis* C: Coccidioidomycosis* *Courtesy of Dr. Paul Getz
Figure 4.30
A: Sporothrix schenckii
(Courtesy of Sandra Arduin,
Michigan Department of
Community Health
)
B: Coccidioidomycosis*
C: Coccidioidomycosis*
*Courtesy of Dr. Paul Getz
(Figure 4.30A)
  • Sporothrix schenckii, dimorphic fungus found in soil, thorns, moss, and bark
  • Risk factors: florist, gardener, farmer, miner, alcoholic
  • Transmission via direct inoculation and inhalation (usually injury from splinter or rose thorn)
  • Different forms:
    • Lymphocutaneous: subcutaneous nodule ± ulceration with ascending lymphatic spread
    • Fixed cutaneous: single subcutaneous nodule, ± ulceration, no lymphatic spread
    • Disseminated: rare; involves bones, joints, meninges, pulmonary, and genitourinary tract
  • Pathology: sporothrix asteroid body (yeast cell with surrounding eosinophilic fringe), also known as Splendore–Hoeppli phenomenon
  • Colony: 25°C fluffy white → turns black; 37°C smooth cream-colored; conidia arranged in groups at end of conidiophore (flower-like) resembling daisies
  • Treatment: itraconazole or supersaturated potassium iodide (SSKI) for lymphocutaneous form