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Pustular Eruptions

»	How does a pustule differ from a vesicle or bulla?
»	How are pustules classified?
»	What is the most common pustular skin eruption?
»	Name the different types of pustular psoriasis. How do they differ?
»	Do any factors precipitate generalized pustular psoriasis?
»	Is pustular psoriasis treated differently than classic plaque-type psoriasis?
»	What is pustular bacterid?
»	Why do some consider pustular bacterid a form of localized pustular psoriasis of the palms and soles?
»	What is subcorneal pustular dermatosis (Sneddon-Wilkinson disease)?
»	Discuss the pathogenesis of subcorneal pustular dermatosis.
»	How is subcorneal pustular dermatosis treated?
»	What is superficial IgA pemphigus?
»	What are the cutaneous findings in reactive arthritis (Reiter’s disease)?
»	Which drugs are commonly associated with pustular drug eruptions?
»	What is acne necrotica miliaris?
»	What is folliculitis decalvans?
»	Discuss the pathogenesis of miliaria pustulosa.
»	How is miliaria pustulosa treated?
»	What is the differential diagnosis of a pustular eruption in a neonate?
»	How do erythema toxicum neonatorum and transient neonatal pustular melanosis differ?
»	What is infantile acropustulosis?
»	What causes infantile acropustulosis?
»	What is the best treatment of infantile acropustulosis?

How is subcorneal pustular dermatosis treated?

Subcorneal pustular dermatosis cannot be cured, but it can be managed. The disease is uncommon enough that good therapeutic studies comparing different treatment modalities are not available. Anecdotal reports have described excellent therapeutic results with dapsone and acitretin. Less frequently used therapies include oral prednisone, topical corticosteroids, sulfapyridine, vitamin E, and ultraviolet B therapy.

Marliere V, Beylot-Barry M, Beylot C, Doutre M: Successful treatment of subcorneal pustular dermatosis (Sneddon-Wilkinson disease) by acitretin: report of a case, Dermatology 199:153–155, 1999.