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Pustular Eruptions

»	How does a pustule differ from a vesicle or bulla?
»	How are pustules classified?
»	What is the most common pustular skin eruption?
»	Name the different types of pustular psoriasis. How do they differ?
»	Do any factors precipitate generalized pustular psoriasis?
»	Is pustular psoriasis treated differently than classic plaque-type psoriasis?
»	What is pustular bacterid?
»	Why do some consider pustular bacterid a form of localized pustular psoriasis of the palms and soles?
»	What is subcorneal pustular dermatosis (Sneddon-Wilkinson disease)?
»	Discuss the pathogenesis of subcorneal pustular dermatosis.
»	How is subcorneal pustular dermatosis treated?
»	What is superficial IgA pemphigus?
»	What are the cutaneous findings in reactive arthritis (Reiter’s disease)?
»	Which drugs are commonly associated with pustular drug eruptions?
»	What is acne necrotica miliaris?
»	What is folliculitis decalvans?
»	Discuss the pathogenesis of miliaria pustulosa.
»	How is miliaria pustulosa treated?
»	What is the differential diagnosis of a pustular eruption in a neonate?
»	How do erythema toxicum neonatorum and transient neonatal pustular melanosis differ?
»	What is infantile acropustulosis?
»	What causes infantile acropustulosis?
»	What is the best treatment of infantile acropustulosis?

Is pustular psoriasis treated differently than classic plaque-type psoriasis?

Most treatments that are used on classic plaque-type psoriasis can also be used for the management of pustular psoriasis. The retinoids, especially acitretin, are particularly effective in pustular psoriasis and are the treatment of choice for generalized pustular psoriasis. More recently, isolated cases have been successfully treated with topical biologic agents such as tacrolimus or parental biologic agents such as infliximab and adalimumab.

Rodriquez GF, Fagundo GE, Cabrera-Oaz R, et al: Generalized pustular psoriasis successfully treated with topical tacrolimus, Br J Dermatol 152:587–588, 2005.

Ghate JV, Alspaugh CD: Adalimumab in the management of palmoplantar psoriasis, Dermatol Online J 15:15, 2009.