Dapsone- Antibacterial and anti-inflammatory (mainly toward neutrophils by inhibition of myeloperoxidase); sulfone family (related to sulfonamides); spectrum: mycobacteria
- Treats: leprosy, dermatitis herpetiformis, autoimmune blistering diseases, erythema elevatum diutinum, pyoderma gangrenosum
- SE: hemolytic anemia (especially if G6PD-deficient), cholestatic jaundice, methemoglobinemia, agranulocytosis (2–12 weeks after continuous treatment), motor peripheral neuropathy, acute psychosis, dapsone hypersensitivity syndrome, photosensitivity
- Pregnancy category C
|
