Erythema Elevatum Diutinum (EED)

Figure 3.42 A: Urticarial vasculitis (Courtesy of Dr. Iris K. Aronson) B: EED* C: Granuloma faciale* * Reprint from Burgdorf WH, Plewig G, Landthaler M, Wolff HH, eds. Braun-Falco’s Dermatology. 3rd ed. Heidelberg: Springer; 2009
Figure 3.42
A: Urticarial vasculitis
(Courtesy of Dr. Iris K.
Aronson
)
B: EED*
C: Granuloma faciale*
* Reprint from Burgdorf WH,
Plewig G, Landthaler M,
Wolff HH, eds. Braun-Falco’s
Dermatology. 3rd ed.
Heidelberg: Springer; 2009
(Figure 3.42B)
  • Presents with red, violaceous or brown papules and plaques favoring extensor surfaces; associated arthralgias
  • Histology: LCV with neutrophilic infiltrate in early lesions; fibrosis and lipid deposits with cholesterol clefts in older lesions
  • Associated with autoimmune diseases, infections (hemolytic strep, HBV, HIV), inflammatory bowel disease, hematologic disorders (IgA monoclonal gammopathy); lesions thought to be related to immune complex deposition in blood vessels with damage to vessels
  • Treatment: d apsone treatment of choice