Mucinous Carcinoma

  • Rare adnexal tumor likely from eccrine gland
  • Often presents as slow-growing nodule, ulcer, or cyst with low metastatic potential, often seen on head or neck
  • Histology: islands of floating ductal structures in a lake of mucin, cells with eosinophilic cytoplasm and hyperchromatic nuclei, mucin separated by thin fibrocollagenous septae
  • Must differentiate primary mucinous carcinoma from metastatic tumors (especially breast or GI origin)
  • Treatment: local excision; high rate of recurrence