Granular Cell Tumor

  • Often solitary, skin-colored to brown-red papulonodule often on head/neck (especially tongue)
  • Histology: poorly demarcated nodule in dermis consisting of large, pale cells with granular cytoplasm and centrally located nucleus, intracytoplasmic granules called pustulo-ovoid bodies of Milian, may see striated skeletal muscle if lesion on tongue