Hirsutism

Figure 3.53 A: Traction alopecia (Courtesy of Dr. Paul Getz) B: Hirsutism in female, cheek (Reprint from Freedberg I, Sanchez M, eds. Current Dermatologic Diagnosis and Treatment. New York: Lippincott Williams & Wilkins; 2001) C: Clitoral hypertrophy in child with virilizing tumor (Reprint from Ibeiro RC, et al. Encyclopedia of Cancer. New York, NY: Springer; 2008)
Figure 3.53
A: Traction alopecia
(Courtesy of Dr. Paul Getz)
B: Hirsutism in female, cheek
(Reprint from Freedberg I,
Sanchez M, eds. Current
Dermatologic Diagnosis and
Treatment. New York:
Lippincott Williams &
Wilkins; 2001
)
C: Clitoral hypertrophy in child
with virilizing tumor
(Reprint from Ibeiro RC, et al.
Encyclopedia of Cancer.
New York, NY: Springer; 2008
)
(Figure 3.53B)
  • Increased number of terminal hairs in women with a male pattern of distribution (unlike hypertrichosis which is an increase in the amount of hair growth anywhere on the body)
  • Androgen-dependent areas include groin, lower abdomen, breasts, chin, lateral cheeks and upper cutaneous lip
  • Causes:
    • Adrenal: congenital adrenal hyperplasia, neoplasm
    • Pituitary: Cushing’s disease, acromegaly, prolactin-secreting adenomas
    • Ovary: ovarian tumor, PCOS
  • Other signs of virilization: deepening of voice, temporal balding, amenorrhea, acne, clitoral hypertrophy (Figure 3.53C)
  • Labs: free/total testosterone, LH, FSH, DHEA-S, ± fasting glucose (if concern for PCOS)
  • Treatment: spironolactone, OCP, topical eflornithine, electrolysis, laser hair removal