»	Basic Science and Immunology
»	Embryology
»	Epidermis
	»	Keratinocytes
	»	Stratum Basale (Germinativum)
	»	Stratum Spinosum
	»	Stratum Granulosum
	»	Stratum Corneum
»	Basement Membrane Zone (BMZ)
	»	Inferior Portion of Basal Keratinocyte
	»	Lamina lucida
	»	Lamina densa
	»	Sublamina densa

Lamina densa

Electron-dense zone below lamina lucida appearing as dense line with closely stippled dots on EM
Type IV collagen: major component and characteristic collagen of BMZ; highly cross-linked sheetlike pattern provides flexibility to basement membrane
Additional components: laminins, entactin (nidogen-1), and heparan sulfate (negatively-charged hydrophilic proteoglycan which provides selective permeability barrier)