Box 13.7 outlines how the disease develops in different parts of the body, T indicating the skin, N lymph nodes, M visceral involvement and B haematological involvement.
| | | | | | Box 13.7 Summary of clinical changes seen in T-cell lymphoma
T1: Patches or plaques <10% body surface area
T2: Patches of plaques >10% body surface area
T3: Tumours
T4: Erythroderma
N0: No palpable nodes
N1: 1 palpable node without histological involvement (dermatopathic)
N2: Non-palpable nodes with histological involvement
N3: Palpable nodes with histological involvement
M0: No visceral disease
M1: Visceral disease
B1: No haematological involvement
B2: Sezary count >5% of total peripheral blood lymphocytes | | | | Source: Whittaker et al. (2003). | |
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Once the clinical level of involvement has been established, this can be summarised using the grading system outlined in Box 13.8.
| | | | | | Box 13.8 Burn and Lambert grading system
Stage IA: T1 N0
Stage IB: T2 N0
Stage IIA: T1/2 N1
Stage IIB: T3 N0/1
Stage III: T4 N0/1
Stage IVA: T any N 2/3
Stage IVB: T any N any M1 | | | | | |
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