What is a Sister Mary Joseph’s nodule?


Sister Mary Joseph’s nodule of the umbilicus. The primary malignancy was never detected.
Fig. 48.6 Sister Mary Joseph’s nodule of the umbilicus. The primary malignancy was never detected.
It is a nodular umbilical metastatic tumor (Fig. 48-6). This sign is named in recognition of Sister Mary Joseph, who was the superintendent of St. Mary’s Hospital in Rochester, Minnesota, and served as the first surgical assistant to Dr. W.J. Mayo. She is credited with recognizing that patients with this finding had a poor prognosis.

Albano EA, Kanter JL: Images in clinical medicine. Sister Mary Joseph’s nodule, N Engl J Med 352:1913, 2005.