Botulinum Toxin Type B

Myobloc contains botulinum toxin type B. It was licensed by the FDA in January 2001 for treatment of cervical dystonia. Elan Pharmaceuticals, the manufacturer of Myobloc, makes no recommendations for its use in cosmetic purposes.However, because it has FDA approval for treatment of cervical dystonia, patients in the United States can consent to off-label use for cosmetic purposes [17]. Moreover, the efficacy and safety of using botulinum toxin type B for cosmetic purposes has been demonstrated in a number of small pilot studies. Overall, the results of these studies found that botulinum toxin type B was an effective treatment for glabellar wrinkles [18, 19, 20, 21, 22, 23], forehead wrinkles [20, 21, 24], and crow’s feet [21, 25, 26]. Further investigation of the safety and efficacy of using botulinum toxin type B for cosmetic purposes will be necessary.