Subepodermal Blistering Diseases
| | | | | | | Table 3-17 Subepidermal Blistering Diseases | | | Disease | | Antigen | | DIF | | IIF on SSS | | | Bullous Pemphigoid | | BPAG2, BPAG1 | | Linear IgG/C3 at BMZ | | Epidermal side | | | Cicatricial Pemphigoid | | BPAG2, β4 subunit, laminin 5 (epiligrin or laminin 332) | | Linear IgG/C3 at BMZ | | Epidermal side
{Anti-epiligrin CP binds DERMAL side} | | | Linear IgA Dermatosis | | 97 kDa (LABD97)
120 kDa (LAD-1) | | Linear IgA at BMZ | | Epidermal side | | | LP Pemphigoides | | BPAG2 | | Linear IgG/C3 at BMZ | | Epidermal side | | | Pemphigoid Gestationis | | BPAG2 | | Linear C3 at BMZ | | Negative | | | Epidermal Bullosa
Acquisita | | Type VII collagen | | Linear IgG at BMZ | | Dermal side | | | Bullous Lupus
Erythematosus | | Type VII collagen | | Linear IgG, IgM, IgA, C3 at BMZ | | Dermal | | | Porphyria Cutanea Tarda | | | | Linear IgG, IgM, IgA, C3 at BMZ and perivascular | | Negative | | | | | | | | | |
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