Pilomatricoma (Calcifying Epithelioma of Malherbe)

• Onset typically in childhood
• Presents as solitary firm, skin-colored to faint blue papule or cyst on face or upper trunk
• Histology: anucleate cornified cells (“ghost” or “shadow” cells), calcification seen in late lesions
• Multiple pilomatricomas may be associated with myotonic dystrophy (β-catenin defect)