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Approaching the Pruritic Patient

»What is the most common symptom of dermatologic disease?
»What is an “itch”?
»Is an itch a separate modality of pain or a submodality of pain?
»What causes an itch?
»Describe the difference between localized and generalized pruritus.
»What is the best approach to evaluation of a patient with localized pruritus?
»What are the common causes of localized pruritus?
»What is notalgia paresthetica?
»What is the physician’s best approach when seeing a patient with generalized pruritus?
»After obtaining a complete history and physical examination, what clinically oriented classification scheme should be followed?
»What are common causes of generalized pruritus?
»How prevalent is an underlying systemic disease in a patient who seeks medical attention for pruritus?
»What is “winter itch”? In which patient population is it common?
»The patient complains that “wool makes me itch” or “I am allergic to wool.” What disease does this patient probably have?
»What treatment should the physician consider if a patient presents with pruritus and “hives”?
»What disease should the physician consider if the patient volunteers that his spouse also suffers from itching?
»Is pruritus in HIV-infected patients common? What are the common causes of pruritus in these patients?
»Which psychiatric disorder often presents with intractable pruritus?
»Which patients with renal failure experience “renal itch”?
»Which patients with liver disease are most likely to experience pruritus? What is the best screening laboratory test?
»What are the common causes of cholestic pruritus?
»Which hematologic disorders are known to present with pruritus?
»Is generalized pruritus a common symptom of endocrine disorders?
»Can itching cause skin disease?
»What is the best symptomatic treatment for a patient with pruritus?

 
 
 

What is the physician’s best approach when seeing a patient with generalized pruritus?

The physician’s most important diagnostic tools are a thorough and systematic history and physical exam. Laboratory testing for systemic disease may be necessary. Common questions include the following:
  • What are the extent, severity, and quality of the itch?
  • When does the pruritus occur, and what is its duration?
  • Are there provocative factors, such as change in temperature or climate?
  • Does the patient have a history of previous skin disorders or allergies?
  • What are the patient’s current medications?
  • Has the patient taken any new oral medications or ingested any new foods?
  • How often does the patient bathe?
  • What products does the patient use on his/her skin?
  • Has the patient used any new skin products?
  • Is there a history of systemic illness?
  • Is health maintenance up to date?
  • Is there a history of psychiatric illness?
  • What is the home environment?
  • Are there pets at home?
  • Does any other family member experience itching?
  • Has there been any recent travel?
  • Is there any emotional stress?
In examining the skin, the physician should focus on whether it is normal or abnormal. Care should be made to differentiate between primary and secondary skin lesions. The primary skin lesion can identify the causal disease, whereas secondary skin lesions are usually reactive from the pruritus itself. Pruritus can occur in the setting of normal skin.