See Table 61-2.
| Table 61-2. Condyloma Accuminatum versus Molluscum Contagiosum |
| | | | CONDYLOMA ACCUMINATA | | MOLLUSCUM CONTAGIOSUM |
| | Clinical appearance | | Soft fleshy cauliflower-like papules. Can be very small with a dome shape and thus difficult to differentiate from molluscum contagiosum | | Small, dome-shaped, typically fleshcolored papules with a central umbilication when squeezed on the lateral edges |
| | Etiology | | Human papilloma virus (HPV)
HPV 6 and 11 are responsible for 90% of these lesions | | DNA poxvirus—molluscum contagiosum virus (MCV). MCV-1 is most prevalent, MCV-2 is most commonly associated with sexually transmitted molluscum contagiosum |
| | Transmission | | Sexually transmitted
Highly contagious | | Sexually transmitted in adults (this disease is common in children on ongenital skin, and is not thought to be sexually transmitted)
Highly contagious; known to be spread through fomites (e.g., wet towels, etc.) |
| | Autoinoculation | | Yes | | Yes |
| | Treatment | | Imiquimod
Podophyllin
Trichloroacetic acid
Laser ablation
Cryosurgery | | Imiquimod
Cantharidin
Trichloroacetic acid
Curettage
Laser ablation
Cryosurgery
Expectant management (many lesions will spontaneously resolve within two years) |
| | Vaccine? | | Quadrivalent vaccine for immunity against HPV
6, 11, 16, and 18 | | None |
