What anatomic locations are most often affected by Lichen planus?

LP may affect both the skin and mucosa. Examination of both areas is essential when the diagnosis of LP is suspected. The frequency of involvement for these areas is somewhat controversial. In general, patients with mucosal disease may not demonstrate skin lesions, but 50% or more of patients with cutaneous disease will demonstrate mucosal lesions. Flexural areas, such as the wrists and ankles, are often involved. Other sites of preferential involvement include the neck, buttocks, sacrum, anogenital region, penis, and buccal or vaginal mucosa.