What are the mechanobullous disorders?

This is a group of disorders, either inherited or acquired, that result in small blisters (vesicle) or large blisters (bulla) that form after trauma to the skin. The most common acquired lesion would be a typical blister that one can develop on a foot after the skin rubs on a shoe or boot. The most common inherited mechanobullous disorders are those that fall into the category of epidermolysis bullosa (EB). Vesicles and bullae develop in these individuals with very minor trauma. The remaining portion of this chapter will deal with EB and its complications.