Annular Elastolytic Giant Cell Granuloma (Actinic Granuloma)

  • Unclear if distinct disease or variant of GA
  • ± Related to inflammation triggered by actinic damage
  • Presents as annular erythematous plaque with slightly atrophic center in sun-exposed areas of older adults; tendency for slow spread
  • Histology: solar elastosis, absence of elastic fibers in center of lesion, elastic fibers adjacent to or within giant cells (elastophagocytosis), granulomatous inflammation
  • Treatment: topical corticosteroids (inconsistent response)