Androgenetic Alopecia
- Males with decreased hair density over bitemporal and vertex of scalp;
females with mid frontoparietal scalp involvement (widened hair part,
‘Christmas tree’ pattern) but preservation of anterior hair line
- Androgen-dependent alopecia; testosterone converted to dihydrotestosterone
(DHT) by 5α-reductase; ↑ activity of DHT and 5α-reductase in men
with androgenetic alopecia
- Histology: normal # of follicles, ↑ vellus hairs, no significant inflammation,
↑ telogen hairs (advanced stages)
- Treatment: minoxidil, finasteride, OCP, spironolactone, hair
transplantation
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