Tuberous Sclerosis
»	Tuberous sclerosis is also known as epiloia. What does this term mean?
»	What is the inheritance of tuberous sclerosis?
»	Where are the genetic defects for tuberous sclerosis?
»	What is the earliest skin sign of tuberous sclerosis?
»	Adenoma sebaceum is a misnomer. What is the correct term for the facial lesions seen in tuberous sclerosis?
»	What are Koenen’s tumors?
»	What is a shagreen patch?
»	What are tubers, and where do they occur?
»	What signs of tuberous sclerosis may be revealed on funduscopic examination?
»	Which cardiac abnormality is characteristic of tuberous sclerosis?
»	Can renal involvement occur in tuberous sclerosis?
»	What is the prognosis for patients with tuberous sclerosis?

Genetic linkage studies of familial cases have demonstrated two separate genes linked to tuberous sclerosis: TSC 1, located at chromosome 9q34, encoding a protein called hamartin, and TSC 2, located at chromosome 16p13.3, encoding a protein called tuberin.

Narayanan V: Tuberous sclerosis complex: genetics to pathogenesis, Pediatr Neurol 29:404–409, 2003.
Curatolo P, Bombardieri R, Jozwiak S: Tuberous sclerosis, Lancet 372:657–668, 2008.