Tuberous Sclerosis
»	Tuberous sclerosis is also known as epiloia. What does this term mean?
»	What is the inheritance of tuberous sclerosis?
»	Where are the genetic defects for tuberous sclerosis?
»	What is the earliest skin sign of tuberous sclerosis?
»	Adenoma sebaceum is a misnomer. What is the correct term for the facial lesions seen in tuberous sclerosis?
»	What are Koenen’s tumors?
»	What is a shagreen patch?
»	What are tubers, and where do they occur?
»	What signs of tuberous sclerosis may be revealed on funduscopic examination?
»	Which cardiac abnormality is characteristic of tuberous sclerosis?
»	Can renal involvement occur in tuberous sclerosis?
»	What is the prognosis for patients with tuberous sclerosis?

Inheritance is autosomal dominant, with high penetrance but variable expression. Up to 60% of cases are said to represent new mutations, but “normal” parents must undergo thorough clinical and radiologic evaluation to exclude subclinical disease.